Spirulina – Effects on Lipid Profile of HIV- infected Antiretroviral Naïve Patients

Researchers from the Department of Physiological Sciences and Biochemistry, Cameroon, have found that spirulina supplementation in HIV-infected antiretroviral naïve patients could significantly reduce the abnormalities in their lipid profile.

spirulina platensis

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Cardiovascular diseases and metabolic alterations are among the major public health concern that has been reported in people with HIV infections.

A single-blind, randomized study was conducted in 169 patients who received spirulina supplementation combined with local diet or local diet only. Age, weight, body mass index (BMI), lipid profile, CD4 count and local food intake variables were assessed in 3, 6 and 12 months.  The average age of the patients was 35.6 ± 9 years and majority of the participants were female.

The results showed that there was a significant increase in HDL-cholesterol and a decrease in total cholesterol, LDL-cholesterol and triglycerides in patients who consumed spirulina. There was also a decrease in the change in atherogenic index.

Thus nutritional supplementation with spirulina combined with a quantitative and qualitative balanced diet for at least six months can retard an exposition to lipid abnormalities in HIV–infected antiretroviral-naive patients.